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Charles
J. Issel, DVM, PhD
Maxwell H. Gluck Equine Research Center
Department of Veterinary Science
University of KentuckyLexington, Kentucky 40546-0099
Our research, continuous since 1974, involves equine infectious
anemia from A to Z. We are working with the national and international
veterinary community to develop and implement sensitive, specific
and practical diagnostic tests for EIA to complement the “Coggins”
test in effective control programs.
At the same time we are studying the intricacies of the EIA
virus (EIAV), a lentivirus, in an attempt to define the genetic
and antigenic variations in this highly mutable agent and
how it impacts protective immunity, i.e., vaccine design and
efficacy. This work is valuable in its own right as well as
being of comparative value as a model for AIDS.

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