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 David
W. Horohov, PhD
Maxwell H. Gluck Equine Research Center
Department of Veterinary Science
University of Kentucky Lexington, Kentucky 40546-0099
Laboratory of Equine Immunology
My research program focuses on the identification and characterization
of equine cytokines and their role in protective and pathologic
immune responses. My research group has cloned, sequenced
and expressed a number of cytokine genes from the horse and
developed assays for their detection. These assays have been
used to better characterize the protective immune responses
of horses to bacterial, viral and parasitic infections, as
well as the pathologic response in autoimmune and allergic
diseases.
We are particularly interested on the effect of age on immune
responses in the horse. Current research focuses on the
developing immune response of foals and how it relates to
their susceptibility to infection. We are also interested
in the effect of advanced age on the immune response of older
horses.
Projects
- Characterization of Interferon-Gamma Production in Foals
- Characterization of the Immune Response of Old Horses
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