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 Ernest
Bailey, PhD
Maxwell H. Gluck Equine Research Center
Department of Veterinary Science
University of Kentucky Lexington, Kentucky 40546-0099
Immunogenetics and Genomics
We are interested in the health and welfare of horses. Immunogenetics
is the study of genetic influences on the innate and adaptive
immune systems which protect horses from infectious diseases.
More recently, technology has made it possible to globally
investigate all the genes in an individual (genomics), their
expression (transcriptomics) and their impact on the cellular
biology and physiology of the horse (proteomics and metabalomics).
Collectively, these global research approaches have been referred
to as “Genomics” after the conceptual advances
initially made possible by the development of “genomics”.
Our research activities include investigations of genes that
control the immune response in horses, development of a genetic
map for horses, studying genetic organization through molecular
and cytogenetic studies, evolution of perissodactyla, characterizing
genes responsible for coat color variation and investigations
on other genes that influence the health and welfare of horses
(hemolytic disease of newborn foals, extreme lordosis, severe
combined immunodeficiency disease, and others.)
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