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 Sergey
C. Artiushin, PhD
Maxwell H. Gluck Equine Research Center
Department of Veterinary Science
University of Kentucky Lexington, Kentucky 40546-0099
My research interests are focused on molecular studies of
Streptococcus equi, Streptococcus zooepidemicus and Leptospira
interrogans.
S. equi causes strangles, a contagious infection of the upper
respiratory tract of horses. S. zooepidemicus is responsible
for metritis in mares and aggravates lower respiratory tract
infections as an opportunistic invader following virus infection.
At present I am involved in two projects relevant to these
pathogens. The first is aimed at identification and analysis
of protective antigens of S. equi; the second is genome sequencing
of S. zooepidemicus W60.
Leptospirosis is a continuing threat to the horse breeder
causing loss due to abortion and stillbirth. Chronic infection
may lead to recurrent uveitis, a major cause of equine blindness.
Control refers both to antibiotic prophylaxis and management
based on identification of seropositive animals by MAT and
detection of leptospira in body fluids using FA and culture.
Presently I am developing more simple, reliable and rapid
methods such as ELISA for identification of seropositive animals
and PCR for detection and identification of leptospira in
body fluids.
Projects
- Immunogenically active proteins of S. equi.
- Genome of S. zooepidemicus W60.
- Development and evaluation of ELISA and PCR for diagnosis of
leptospira infection in horses.
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